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AP1867

 

CAS: 195514-23-9

 

Chemical Name:  dTAG acid; 3-(3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)-piperidine-2-carbonyl)oxy)propyl)phenoxy)propanoic acid

 

 

GLXC-12448        Cat No: GLXC-12448

 

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

Precursor for the dTAG system which pairs a novel degrader of FKBP12(F36V) with expression of FKBP12(F36V) in-frame with a protein of interest, showiing superior antiproliferative effect of pan-BET bromodomain degradation over selective BRD4 degradation, characterize immediate effects of KRAS(G12V) loss on proteomic signaling, and demonstrate rapid degradation in vivo

 

Analytical data click for PDF file

 

 

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