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CAS: N/A
Chemical Name: 2-Chloro-N-(4-(N-(3-cyanothiophen-2-yl)sulfamoyl)phenyl)acetamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
First-in-class covalent allosteric SHP1 inhibitor, inactivating SHP1 by covalently binding to a non-conserved and cryptic Cys480 far away from the active site
References:
https://onlinelibrary.wiley.com/doi/10.1002/anie.202525126
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