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SHP1 inhibitor M029

 

CAS: N/A

 

Chemical Name: 2-Chloro-N-(4-(N-(3-cyanothiophen-2-yl)sulfamoyl)phenyl)acetamide

 

 
GLXC-90240For Lab R&D Uses Only
        Cat No: GLXC-90240

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class covalent allosteric SHP1 inhibitor, inactivating SHP1 by covalently binding to a non-conserved and cryptic Cys480 far away from the active site

 

References:

https://onlinelibrary.wiley.com/doi/10.1002/anie.202525126

https://acs.digitellinc.com/p/s/discovery-of-the-first-potent-and-orally-bioavailable-shp1-covalent-inhibitor-for-cancer-immunotherapy-598096

 

Analytical data click for PDF file

 

 

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