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Glixx Laboratorie
CAS: 2772613-37-1
Chemical Name: 5-((18-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-18-oxo-3,6,9,12,15-pentaoxaoctadecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity: >98% (HPLC)
Novel EGFR degrader, selectively degrading the mutant but not the WT EGFR through both ubiquitination/proteasome and autophagy/lysosome pathways
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00345
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