Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 7-(4-((4-((3-(N-(tert-Butyl)sulfamoyl)phenyl)amino)-5-methylpyrimidin-2-yl)amino)phenoxy)-N-hydroxyheptanamide
Purity: >98% (HPLC)
Novel dual JAK/HDAC inhibitor, potently inhibiting HDAC3/6 and JAK1/2 at nanomolar levels and exhibiting splendid selectivity for the JAK2 against a panel of 76 kinases, presenting remarkable antiproliferative activity in both hematological malignancies and solid cancers
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00036
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