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Glixx Laboratorie
CAS: 1973403-00-7
Chemical Name: (2S,4R)-1-[(2S)-2-(2-[4-[4-(4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel PROTAC, acting as an androgen receptor degrader, outperforming enzalutamide in cellular models of prostate cancer drug resistance
Ref: https://www.nature.com/articles/s42003-018-0105-8
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