Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1448346-43-7
Chemical Name: (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(3,5-difluorophenyl)-5-oxopyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel potent and selective, orally available IDH1 mutant inhibitor, inhibiting cell proliferation (human cell lines transfected with IDH1 R132H) with IC50 values of 0.76 nM (HT-1080), 0.74 nM (U87-MG) and 1.75 nM (TF1)
Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900343/
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