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CAS: 467214-21-7
Chemical Name: 17-DMAG; KOS-1022; NSC-707545; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-21-[2-(Dimethylamino)ethylamino]-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate hydrochloride
Cat No: GLXC-07137
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Inhibitor of HSP90, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Alvespimycin&sort=date
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