Glixx Laboratories Inc

               Your exclusive source for bioactive molecules

Glixx Laboratorie

 

   sales@glixxlabs.com      Toll-Free: (855)Go-Glixx   Tel: 781-333-5348    Fax: 781-333-5368 
Keap1 Degrader I-d

 

CAS: N/A

 

Chemical Name: PROTAC I-d; (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-Cyano-N-(5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)pentyl)-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-hexadecahydropicene-4a(2H)-carboxamide

 

 
GLXC-27556For Lab R&D Uses Only
        Cat No: GLXC-27556

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel Keap1 degrader, exhibiting optimal Keap1 degradation activity, increasing the Nrf2 level, alleviating oxidative stress in free fatty acid-induced AML12 cells and the liver of mice fed with a methionine-choline-deficient diet, displaying significant advantages in inhibiting hepatic steatosis, steatohepatitis, and fibrosis in the in vivo and in vitro models of NAFLD

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00822


Analytical data click for PDF file

 

 

Place an order!

Price & Availability


POA
 








Bulk inquiry contact:
sales@glixxlabs.com
service@glixxlabs.com