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Glixx Laboratorie
CAS: 2413693-96-4
Chemical Name: (R)-4-((2-(((1,4-Dimethyl-1H-pyrazol-3-yl)(1-methylcyclopentyl)methyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-3-hydroxy-N,N-dimethylpicolinamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent C-C chemoattractant cytokine (chemokine) receptor 6 (CCR6) antagonist, distinguishing between homologous chemokine receptors, increasing basal circulating CCR6+ T cells, and ameliorates interleukin-23-induced skin inflammation
References:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c01946
https://jpet.aspetjournals.org/content/386/1/80.long
Analytical data

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