Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 865783-99-9
Chemical Name: ON-014185; [2-Methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel inhibitor of cyclin D1 accumulation in cancer cells, also inhibiting eIF4E and downregulating the expression of eIF4E itself and its two complex partners eIF4A and G, as well as other eIFs (eg, eIF1A, eIF2α, eIF3A, eIF3B, eIF5, and eIF6)
Reference:
https://www.sciencedirect.com/science/article/pii/S1043661825000854
https://www.jidonline.org/article/S0022-202X(23)02917-2/fulltext
https://cancerres.aacrjournals.org/content/75/15_Supplement/1649
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