Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 878581-60-3
Chemical Name: GSK1286863A; N-(8-Quinolinyl)-2-pyrazinecarboxamide
Purity: >98% (HPLC)
Novel stress response and autophagy inducer, showing significant in vivo efficacy in a pancreatic cancer xenograft model, significantly increasing the expression of HSPA5, DDIT3, TRIB3, and ATF3 genes, activating the stress response pathway, also significantly increasing in the expression of WIPI1, HERPUD1, GABARAPL1, and MAP1LC3B, implicating autophagy
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c02207
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