Glixx Laboratories Inc

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Glixx Laboratorie

 

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QN523

 

CAS: 878581-60-3

 

Chemical Name: GSK1286863A; N-(8-Quinolinyl)-2-pyrazinecarboxamide

 

 
GLXC-25600For Lab R&D Uses Only
        Cat No: GLXC-25600

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel stress response and autophagy inducer, showing significant in vivo efficacy in a pancreatic cancer xenograft model, significantly increasing the expression of HSPA5, DDIT3, TRIB3, and ATF3 genes, activating the stress response pathway, also significantly increasing in the expression of WIPI1, HERPUD1, GABARAPL1, and MAP1LC3B, implicating autophagy

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c02207

 

Analytical data click for PDF file

 

 

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