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WS-691

 

CAS: 2035417-32-2

 

Chemical Name: 2-(1H-Benzimidazol-2-ylmethylsulfanyl)-N-(4-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

 

 
GLXC-23335For Lab R&D Uses Only
        Cat No: GLXC-23335

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent and orally active ABCB1 modulator capable of overcoming MDR, stabilizing ABCB1 by directly binding to ABCB1, stimulating the activity of ABCB1 ATPase without inhibitory activity against CYP3A4, increasing the sensitivity of SW620/Ad300 cells to PTX in vivo without observed toxicity

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01741

 

Analytical data click for PDF file

 

 

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