Glixx Laboratories Inc

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TAH-19

 

CAS: N/A

 

Chemical Name: 6GG; 4-[6-[6-Chloro-3-[3-[(4-chlorophenyl)methyl]-5-(4-fluorophenyl)imidazol-4-yl]-1H-indole-2-carbonyl]oxyhexylamino]-4-oxobutanoic acid

 

 
GLXC-22125For Lab R&D Uses Only
        Cat No: GLXC-22125

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent p53-MDM2/X antagonist, inhibiting MDM2 potently with a Ki value of 58 nmol/L, inducing accumulation of p53, p21 and MDM2, inhibiting cell cycle progression of U-2 OS cells at G1 phase in a p53-dependent manner

 

Ref: https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.7b00104

 

Analytical data click for PDF file

 

 

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