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CAS: 879484-94-3
Chemical Name: TDP-222669; (S)-2-(4-Chlorophenyl)-2-((R)-3-(4-chlorophenyl)-7-iodo-2,5-dioxo-1,2,3,5-tetrahydro-4H-benzo[e][1,4]diazepin-4-yl)acetic acid
Purity: >98% (HPLC)
Novel inhibitor of the p53-Hdm2 protein-protein interaction, dose-dependently stabilized P53 and increased P21 and MDM2 expression in JAR choriocarcinoma cells, inducing the p53 regulated gene (PIG-3) and caspase activity
Ref: https://www.sciencedirect.com/science/article/pii/S0960894X06004215
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