Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Glixx Laboratorie
CAS: 2370013-12-8
Chemical Name: DZD9008; N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide
Purity: >98% (HPLC)
Novel potent ErbBs (EGFR, Her2, especially mutant forms) inhibitor, showing IC50s of 20.4, 20.4, 1.1, 7.5, and 80.4 nM for EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and Her2 Exon20 YVMA, and EGFR WT A431, respectively, also inhibiting BTK
References:
1) https://www.tandfonline.com/doi/abs/10.1080/03007995.2022.2083326
Place an order!
POA | in-stock | ||
Bulk inquiry contact: | |||
sales@glixxlabs.com |
|||
service@glixxlabs.com |