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CAS: 38485-94-8
Chemical Name: 6-Chloro-N-(4-hydroxyphenyl)-2-oxo-2H-chromene-3-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel dual LonP1 and CT-L proteasome inhibitor, subsequently inducing ROS accumulation and autophagy-dependent cell death in high-grade IDH1 mutated astrocytoma lines, enhancing synergy with the commonly used chemotherapeutic temozolomide (TMZ)
Reference:
https://www.biorxiv.org/content/10.1101/2023.04.13.536816v1.full
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