Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2060610-53-7
Chemical Name: (2R)-2-(5-Fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide
Purity: >98% (HPLC)
Novel EGFR mutant allosteric inhibitor, targeting EGFRL858R/T790M/C797S signaling in vitro and in vivo
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381467/
2) https://cancerdiscovery.aacrjournals.org/content/9/7/926.long
3) https://link.springer.com/article/10.1007/s43440-020-00131-0
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