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CAS: N/A
Chemical Name: 2-(4-(Difluoromethyl)-6-((4-((4-(hydroxymethyl)piperidin-1-yl)methyl)phenyl)ethynyl)-7-methyl-2H-indazol-2-yl)-2-(6',7'-dihydrospiro[cyclopropane-1,5'-pyrrolo[1,2-c]imidazol]-1'-yl)-N-(thiazol-2-yl)acetamide
Purity: >98% (HPLC)
The first allosteric EGFR inhibitor that demonstrates robust tumor regression in a mutant EGFRL858R/C797S tumor model
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00893
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