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CAS: N/A
Chemical Name: (S)-2-(2-(4-(5-((2-(4-Aminophenyl)-7-methoxy-5-oxo-5,11a-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-8-yl)oxy)pentyl)piperazin-1-yl)ethyl)-1H-dibenzo[de,h]isoquinoline-1,3(2H)-dione
Purity: >98% (HPLC)
Novel highly potent antibody payload with an IC50 of 0.17-0.94 nM, inducing DNA damage and leading to tumor cell cycle arrest and apoptosis.
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00471
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