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CAS: 2098487-75-1
Chemical Name: 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide
Purity: >98% (HPLC)
Novel SirReal-based PROTAC, inducing isotype-selective Sirt2 degradation, resulting in the hyperacetylation of the microtubule network coupled with enhanced process elongation
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.6b01872
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