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CAS: 308359-57-1
Chemical Name: Zalypsis; PM-00104; [(1R,2S,13R,15S,16S)-15,22-Dihydroxy-21-methoxy-6,20,24-trimethyl-13-[[[(E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoyl]amino]methyl]-8,10-dioxa-14,24-diazahexacyclo[14.7.1.02,14.04,12.07,11.018,23]tetracosa-4,6,11,18(23),19,21-hexaen-5-yl] acetate
For Lab R&D Uses Only
Purity: >98% (HPLC)
Potent anticancer tetrahydroisoquinoline alkaloid, being able to form a covalent bond with the amino group of a guanine in selected triplets of DNA duplexes and eventually give rise to double-strand breaks
References:
https://pubmed.ncbi.nlm.nih.gov/?term=PM00104&sort=date
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