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Glixx Laboratorie
CAS: 2002381-25-9
Chemical Name: 6,7-Dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine
Cat No: GLXC-09235
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel modulator of KSR-dependent MAPK signaling, antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK (mitogen-activated protein kinase)
References:
https://www.tandfonline.com/doi/10.1080/14728222.2017.1311325
https://www.nature.com/articles/nature19327
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