Glixx Laboratories Inc

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VRT-534

 

CAS: 926664-32-6

 

Chemical Name: VRT534; 1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-((S)-(2-chlorophenyl)((R)-3-hydroxypyrrolidin-1-yl)methyl)thiazol-2-yl)cyclopropane-1-carboxamide

 

 
GLXC-27477For Lab R&D Uses Only
        Cat No: GLXC-27477

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel restorer of the mutated connexin 26 (Cx26) function, exhibiting sensitivity toward the HSP90 inhibitor radicicol and dose-responsive binding to recombinant WT Cx26 and mutant Cx26K188N with half maximal effective concentration values of 19 and ~5 μM, respectively

 

References:

https://pubs.acs.org/doi/10.1021/acsptsci.3c00056

https://www.sciencedirect.com/science/article/abs/pii/S109455391530016X

https://www.sciencedirect.com/science/article/pii/S1074552114001082

 

 

Analytical data click for PDF file

 

 

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