Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2143452-20-2
Chemical Name: S37a; (4aS,5S,5aR,8aR,9R,9aS,10R)-7,10-Diphenyl-3,4a,5,5a,8a,9,9a,10-octahydro-5,9-methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel highly selective negative allosteric modulator (NAM) of thyrotropin receptor (TSHR), binding at the ectodomain/TMD interface, between the converging helix, ECL1 and the IA, noncompetitively inhibiting PAM-C2-activation
References:
https://molpharm.aspetjournals.org/content/96/4/452.long
https://www.liebertpub.com/doi/10.1089/thy.2018.0349
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