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MRGPRX1 PAM 1t

 

CAS: 2764889-60-1

 

Chemical Name: 6-(tert-Butyl)-5-(3,4-dichlorophenyl)-4-(2-(trifluoromethoxy)phenoxy)thieno[2,3-d]pyrimidine

 

 
GLXC-25197For Lab R&D Uses Only
        Cat No: GLXC-25197

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel positive allosteric modulator (PAM) of mas-related G protein-coupled receptor X1 (MRGPRX1), reducing behavioral heat hypersensitivity in humanized MRGPRX1 mice, demonstrating the therapeutic potential in treating neuropathic pain

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01709

 

Analytical data click for PDF file

 

 

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