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CAS: 2140289-17-2


Chemical Name: BET-d246; 4-((3-Cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino)-7-(3,5-dimethylisoxazol-4-yl)-N-(3-(2-(2-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)ethoxy)ethoxy)propyl)-6-methoxy-9H-pyrimido[4,5-b]indole-2-carboxamide


GLXC-20765For Lab R&D Uses Only
        Cat No: GLXC-20765


Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)



Product Description:

Novel potent BET degrader, targeting Merkel cell carcinoma (MCC) significantly more sensitive than BET inhibitor treatment, resulting in a loss of "MCC signature" genes but not MYC expression as previously described irrespective of Merkel cell polyomavirus (MCPyV) status


Analytical data click for PDF file



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