Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2140301-97-7 (free base: 1792180-81-4)
Chemical Name: Ritlecitinib malonate; 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-piperidin-1-yl]-propenone malonate
Cat No: GLXC-09605
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Npvel potent JAK3-selective inhibitor, selectively targeting garmma-c cytokine pathways while preserving JAK1-dependent anti-inflammatory signaling such as the IL-10 suppressive functions following LPS treatment in macrophages and the suppression of TNFa and IL-1ß production in IL-27-primed macrophages
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Ritlecitinib+&sort=date
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