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CAS: N/A
Chemical Name: N-((4,5-Difluoro-1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(naphthalen-2-yl)-9H-purin-6-amine
Purity: >98% (HPLC)
Novel potent and highly isoform-selective inhibitor of casein kinase 1ε ((58 nM) vs casein kinase 1δ (>10000 nM), displaying nanomolar growth inhibition of bladder cancer cells and inhibiting the phosphorylation of 4E-BP1 in T24 cells
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01180
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