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Aß aggregation inhibitor DS2

 

CAS: N/A

 

Chemical Name: Ac-(2,2-bis((2-trifluoromethylphenyl-1H-1,2,3-triazol-4-yl)methyl))Gly-Leu-Val-OMe

 

 
GLXC-27247For Lab R&D Uses Only
        Cat No: GLXC-27247

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel inhibitor of Aß aggregation with an IC50 value of 2.43 ± 0.05 μM, disaggregating preformed Aß42 fibrils, chelating metal ions, inhibiting metal-mediated Aß aggregation, significantly controling reactive oxygen species production, and reducing oxidative stress, exhibiting very low cytotoxicity and significantly ameliorating the Aß-induced toxicity in differentiated neuroblastoma cells, SH-SY5Y

 

Reference:

https://pubs.acs.org/doi/10.1021/acschemneuro.3c00041


Analytical data click for PDF file

 

 

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