Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: Ac-(2,2-bis((2-trifluoromethylphenyl-1H-1,2,3-triazol-4-yl)methyl))Gly-Leu-Val-OMe
Purity: >98% (HPLC)
Novel inhibitor of Aß aggregation with an IC50 value of 2.43 ± 0.05 μM, disaggregating preformed Aß42 fibrils, chelating metal ions, inhibiting metal-mediated Aß aggregation, significantly controling reactive oxygen species production, and reducing oxidative stress, exhibiting very low cytotoxicity and significantly ameliorating the Aß-induced toxicity in differentiated neuroblastoma cells, SH-SY5Y
Reference:
https://pubs.acs.org/doi/10.1021/acschemneuro.3c00041
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