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Glixx Laboratorie
CAS: 2944463-16-3
Chemical Name: Methyl 3-((2-oxo-2-((2-(phenylthio)phenyl)amino)ethyl)amino)benzoate
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel anti-osteoporosis agent, targeting NFATc1 translocation, blocking the formation of F-action belts and bone resorption in a concentration-dependent manner, exhibiting promising bioactivity, with an IC50 value of 322.9 nM, which was ~15-fold better than PMSA-3-Ac in suppressing osteoclastogenesis in vitro
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00114
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