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Glixx Laboratorie
CAS: N/A
Chemical Name: 2-Hydroxy-4-((4-(naphthalen-2-yl)thiazol-2-yl)amino)benzoic acid
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel selective allosteric modulator of the protein kinase CK2, inducing apoptosis and cell death in 786-O renal cell carcinoma cells (EC50 = 5 µM) and inhibiting STAT3 activation even more potently than the ATP-competitive drug candidate CX-4945
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b01765
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