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CAS: 2380000-55-3
Chemical Name: ß-Naphthoflavone-(+)-JQ1 conjugate; (S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(2-(2-(2-((4-(1-oxo-1H-benzo[f]chromen-3-yl)benzyl)oxy)ethoxy)ethoxy)ethyl)acetamide
Purity: >98% (HPLC)
Novel chimeric degrader against bromodomain-containing (BRD) proteins, inducing the interaction of AhR and BRD proteins and displaying effective anticancer activity that correlated with protein knockdown activity
Ref: https://pubs.acs.org/doi/10.1021/acschembio.9b00704
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