Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Glixx Laboratorie
CAS: N/A
Chemical Name: 9-(((2R,3R,4S)-6-Carboxy-3,4-dihydroxy-3,4-dihydro-2H-pyran-2-yl)oxy)-1,7,14-trihydroxy-13-oxo-3-(2-oxopropyl)-6,13-dihydro-5H-naphtho[1,2-b]xanthene-2-carboxylic acid
Purity: >98% (HPLC)
First-in-class marine natural C9orf72 GGGGCC (G4C2) ligand, selectively binding to DNA and RNA G4C2 G4s, showing the highest permeability and lowest cytotoxicity to live cells, dramatically reducing G4C2 EHR-caused cell death, diminishing G4C2 RNA foci in (G4C2)29-expressing Neuro2a cells, and significantly eliminating ROS in HT22 cells
Ref: https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c00654
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