Glixx Laboratories Inc

               Your exclusive source for bioactive molecules

Glixx Laboratorie

 

   sales@glixxlabs.com      Toll-Free: (855)Go-Glixx   Tel: 781-333-5348    Fax: 781-333-5368 
MS3227

 

CAS: N/A

 

Chemical Name: 2-((3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-((4-(10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoyl)piperazin-1-yl)sulfonyl)-3,3-dimethylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid

 

 
GLXC-27638For Lab R&D Uses Only
        Cat No: GLXC-27638

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel MDM2 degrader, recruiting the E3 ligase Von Hippel-Lindau, resulting in proteasome-dependent degradation of MDM2, activating the p53 pathway with higher potency than standard inhibitor, being active in primary leukemia specimens, cooperating with other leukemia therapies for greater efficacy

 

Reference:

https://www.nature.com/articles/s41375-022-01735-6


Analytical data click for PDF file

 

 

Place an order!

Price & Availability


POA
 








Bulk inquiry contact:
sales@glixxlabs.com
service@glixxlabs.com