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Glixx Laboratorie
CAS: N/A
Chemical Name: 2-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2H-indazole-7-carboxamide
Purity: >98% (HPLC)
Novel degrader of the PARP1 protein through the proteasome pathway, inhibiting DNA damage repair, activating the cyclic GMP-AMP synthase/stimulator of the interferon gene (cGAS/STING) pathway of innate immunity, enhancing T cell killing of tumor cells
Ref: https://www.sciencedirect.com/science/article/abs/pii/S0968089622003054
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