Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1621519-26-3
Chemical Name: TQ-B3139. CT-711; 5-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-4'-methoxy-6'-[(2S)-2-methylpiperazin-1-yl][3,3'-bipyridin]-6-amine
Purity: >98% (HPLC)
Novel potent and orally active inhibitor of ALK (IC50s of 1.96 nM, 35.1 nM, and 61.3 nM for WT and mutated L1196M and G1269S-ALK)
References:
https://www.ejcancer.com/article/S0959-8049(22)00388-4/fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129499/
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