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TTK PROTAC 8e

 

CAS: 2953426-43-0

 

Chemical Name: N-((1s,4s)-4-(2-((4-(4-(6-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)hex-5-ynoyl)piperazin-1-yl)-2-methoxyphenyl)amino)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)cyclohexyl)propionamide

 

 
GLXC-25293For Lab R&D Uses Only
        Cat No: GLXC-25293

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class potent threonine tyrosine kinase (TTK) PROTAC, demonstrating strong TTK degradation in COLO-205 human colorectal cancer cells with DC50 values of 1.7 nM

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01768

 

Analytical data click for PDF file

 

 

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