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Glixx Laboratorie
CAS: 2676177-63-0
Chemical Name: (5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-Butyl)-18-cyclopentyl-29-(3,5-difluoro-4-(trifluoromethyl)phenethyl)-36-ethyl-11-isobutyl-N,N,5,6,12,16,19,33-octamethyl-35-(4-methylbenzyl)-4,7,10,13,17,20,23,28,31,34,37-undecaoxotetratriacontahydro-2H,4H-spiro[azeto[2,1-u]pyrrolo[2,1-i][1,4,7,10,13,16,19,22,25,28,31]undecaazacyclotetratriacontine-21,1'-cyclopentane]-15-carboxamide
Purity: >98% (HPLC)
Novel cyclic peptide RAS inhibitor for the treatment of locally advanced or metastatic solid tumors, inhibiting protein-protein interaction between RAS and GEF to retain RAS in an inactive state
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01296
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