Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 790702-57-7
Chemical Name: ML414; 5-(dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide
Cat No: GLXC-09454
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel cell-permeable inhibitor of oligosaccharyltransferase (OST), blocking cell-surface localization and signaling of the epidermal growth factor receptor (EGFR) glycoprotein in non-small-cell lung cancer cells, but selectively arresting proliferation in only those cell lines that are dependent on EGFR (or fibroblast growth factor, FGFR) for survival
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854512/
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393272/
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