Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1347749-97-6
Chemical Name: UNC10217938; Ethyl (8-((2-(dimethylamino)ethyl)amino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl)carbamate
Purity: >98% (HPLC)
Novel destabilizer of the endosome membrane, enhancing the endosome-leakage activity of cell-penetrating peptides and facilitating the endosomal escape of macromolecules initially internalized by mammalian cells via endocytosis
References:
1) https://pubs.acs.org/doi/10.1021/acschembio.9b00585
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829638/
3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605259/
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